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Anti-IL2RA Antibody Fab (CAT#: MOM-18155-F(P))

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human IL2RA Antibody Fab Fragment MOM-18155-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment binds selectively to Human CD25, expressed in E. coli
  • Target
  • CD25
  • Type
  • Fab Fragment based on Mouse IgG1 - kappa
  • Immunogen
  • Human leucocytes.
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Predicted N terminal
  • H chain: QVQLVQS; L Chain: EIVLTQS
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • Function
  • drug binding; interleukin-2 binding; interleukin-2 receptor activity; receptor activity;
  • Synonyms
  • IL2RA; interleukin 2 receptor, alpha; IL2R; interleukin-2 receptor subunit alpha; CD25; p55; IL2-RA; IL-2-RA; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; TCGFR; IDDM10;

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